The 2025 STXBP1 Summit, hosted by the European STXBP1 Consortium (ESCO), will take place in Heidelberg, Germany. This significant event, scheduled from October 8-11, 2025, includes a Research Roundtable from October 8-10, followed by a Family Summit on October 11. The summit aims to bring together researchers, clinicians, and families affected by STXBP1 disorders to discuss advancements, share knowledge, and foster collaboration. Set in the historic and picturesque city of Heidelberg, the event promises to be a pivotal moment for the STXBP1 community, driving forward the understanding and treatment of this rare neurological condition. Save the date for this essential gathering!